Searchable abstracts of presentations at key conferences in endocrinology

ea0032p753 | Obesity | ECE2013

Chronic central administration of amylin decreases fat mass but does not modify body weight

Touceda David Gonzalez , Pico Amparo Romero , Piedra Monica Imbernon , Couto Begona Porteiro , Tarrio Daniel Beiroa , Lopez Miguel , Nogueiras Ruben , Dieguez Carlos

Aims (objectives): Energy intake and expenditure are regulated by different signals. One of the molecules implicated is islet amyloid polypeptide (IAPP or amylin), one of the major secretory products of β-cells of the pancreatic islets of Langerhans. It is a peptide that inhibits insulin and glucagon secretion, and can also act through the brain decreasing food intake and inhibiting gastric emptying. In this study, we investigated the potential effects of the chronic cent...